morpheus heat map tool  (Broad Institute Inc)

Journal: PLoS ONE

Article Title: Temporal transcriptome analysis suggest modulation of multiple pathways and gene network involved in cell-cell interaction during early phase of high altitude exposure

doi: 10.1371/journal.pone.0238117

Figure Lengend Snippet: ( a ) Differentially expressed genes represented as bar graph–comparative up regulated and down regulated bars of all high altitude time points in comparison to basal ( b ) Venn diagram show the overlap of high altitude time series DEGs in comparison to basal. Overlap is shown among and between all high altitude time points. ( c ) Hierarchical clustering of the differentially expressed genes depicting 4 high altitude time points as compared with control. Expression values of specific genes (in technical replicates) are represented by colour intensities as shown in the reference colour key. Euclidean distance measure hierarchical clustering algorithm was used. Heat map was constructed online using CIMiner tool. ( d ) Group wise hierarchical clustering of the differentially expressed genes depicting 4 high altitude time points. Expression values of specific genes are represented by colour intensities as shown in the reference colour key. Abbreviations: HAD3, high altitude day 3; HAD7, high altitude day 7; HAD14, high altitude day 14; HAD21, high altitude day 21.

Article Snippet: The file was uploaded to the Morpheus heat map building tool available from the Broad Institute.

Techniques: Comparison, Control, Expressing, Construct